SyncoZymes

oloa

Ketoreductase (KRED)

Fa'amatalaga Puupuu:

E uiga i le Ketoreductase

Enzymes: O macromolecular biological catalysts, o le tele o enzymes o polotini.

Ketoreductase: E taʻua foʻi o le "Carbonyl reductase", o enzymes e faʻamalosia ai le toe faʻafoʻiina o le redox i le va o aldehydes / ketones ma ava malosi, ma manaʻomia coenzymes e pei o le H transmitter e pei ole NADH poʻo le NADPH.E tolu vaega autu o KRED: Short-chain Dehydrogenase / Reductases (SDRs), Medium-chain Dehydrogenases / Reductases (MDRs), ma Aldo-KetoReductases (AKRs).O galuega fa'atino a le tolu e tutusa, ae o le fausaga ma meatotino e fai si eseese.

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Fa'amatalaga Oloa

Faailoga o oloa

E uiga i le Ketoreductase:

KRED mai SyncoZymes: E 191 ituaiga o KRED enzyme oloa (Numera pei ES-KRED-101~ES-KRED-291) atiaʻe e SyncoZymes.E mafai ona fa'aoga lautele le SZ-KRED i le fa'aitiitiga o aldehydes, beta-ketone esters, α-ketone esters ma ketones.

Ituaiga tali fa'amamafa:

Ketoreductase KRED2

Fa'amatalaga o oloa:

Ketoreductase KRED
Enzymes Code o oloa Fa'amatalaga
Enzyme Powder Enzyme Powder se seti o 187 Ketoreductases, 50 mg taʻitasi 187 mea * 50mg / mea, poʻo isi aofaʻi
Pusa su'esu'e (SynKit) ES-KRED-18100 se seti o 181 Ketoreductases, 1 mg taitasi 181 aitema * 1mg / mea

Tulaga lelei:

★ maualuga substrate specificity.
★ Malosi le filifilia o chiral.
★ Fa'aliliuga maualuga maualuga.
★ Faʻaitiitia mea faʻatau.
★ Tulaga tali malie.
★ Siosiomaga.

Fa'atonuga mo le fa'aoga:

➢ E tatau ona faia le su'esu'ega o le enzyme mo mea'ai fa'apitoa ona o le tulaga fa'apitoa o le mea'ai, ma maua se enzyme e fa'agasolo ai le mea'ai fa'atatau i le fa'agata sili ona lelei.
➢ 'Aua ne'i fa'afeso'ota'i i tulaga ogaoga e pei o le: maualuga le vevela, maualuga/maualalo le pH ma so'o so'o fa'atasi ma le maualuga maualuga.
➢ E masani lava, o le faiga e tali atu ai e tatau ona aofia ai le mea'ai, vaifofo pa'u, coenzymes(NAD(H) po'o le NADP(H) ), coenzyme regeneration system(eg kulukose ma le glucose dehydrogenase).
➢ E tatau ona toe fa'aopoopo le KRED i le faiga fa'afoliga, pe a uma ona fa'afetaui le pH ma le vevela i le tulaga e tali mai ai.
➢ O ituaiga uma o KRED e iai tulaga e sili ona lelei e tali atu ai, o lea e tatau ai ona su'esu'eina ta'ito'atasi.

Fa'ata'ita'iga o Talosaga:

Faataitaiga 1(1):

Ketoreductase KRED3

Faataitaiga 2(2):

Ketoreductase KRED4

Fa'asinomaga:

1. Li Z, Liu WD, Chen X, e tal.Tetrahedron, 2013, 69, 3561-3564.
2. Ni Y, Li CX, Ma HM, e tal.Appl Microbiol Biotechnol, 2011, 89: 1111-1118.


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