Imine reductase (IRED)
Fa'amatalaga Puupuu:
E uiga ile Imine reductase
ES-IRED: O se vasega o enzymes e faʻamalosia le faʻaititia o le C=N faʻamau i le CN bond.E a'afia i le redox enzyme, ma le coenzyme NADPH mo le felauaiga o le hydrogen.E tusa ai ma le manaʻoga sili o oloa, e mafai ona vaevaeina i R-IRED ma S-IRED.Syncozymes atiina ae 15 imine reductases (numbIRED ES-IRED-101-ES-IRED-115), lea e mafai ona faaaoga lautele i regioselective ma stereoselective faaitiitia o imines e saunia chiral amines.
Ituaiga tali fa'amamafa:
Mobile/Wechat/WhatsApp: +86-13681683526
I-Meli:lchen@syncozymes.com
| Enzymes | Code o oloa | Fa'amatalaga |
| Enzyme Powder | ES-IRED-101~ ES-IRED-114 | se seti o 14 Imine Reductase, 50 mg taʻitasi |
| 96-Pusa Su'esu'ega Enzyme Well | ES-IRED-1400 | se seti o 14 Imine Reductase, 1 mg taʻitasi |
★ maualuga substrate specificity.
★ Malosi le filifilia o chiral.
★ Liliu maualuga.
★ Faʻaitiitia mea faʻatau.
★ Tulaga tali malie.
★ Siosiomaga.
➢ E masani lava, o le faiga e tali atu ai e tatau ona aofia ai le mea'ai, vaifofo pa'u, enzyme, coenzyme, ma le coenzyme regeneration system.
➢ O ituaiga uma o ES-IRED e fetaui ma tulaga eseese o tali sili ona lelei e tatau ona su'esu'eina ta'ito'atasi.
➢ Fa'asa'o maualuga le mea'ai po'o se oloa e mafai ona fa'alavelaveina le gaioiga a le ES-IRED.Ae ui i lea, e mafai ona faʻamalolo le faʻalavelave e ala i le faʻaopoopoina o se vaega o substrate.
Fa'ata'ita'iga 1(Biosynthesis o chiral 2-methyl pyrrolidine)(1):
Fa'ata'ita'iga 2(Biosynthesis o amine lona lua)(2):
Fa'ata'ita'iga 3 (Fa'aitiitiga o Cyclic Imines)(3):
Taofi le 2 tausaga i lalo -20℃.
Aua ne'i fa'afeso'ota'i i tulaga ogaoga e pei o le: maualuga le vevela, maualuga/maualalo le pH ma le maualuga o le fa'aogaina o so'o.
1. Scheller PN, Fademrecht S, Hofelzer S, et al.ChemBioChem, 2014, 15, 2201-2204.
2. Wetzl D, Gand M, Ross A, et al.ChemCatChem, 2016, 8, 2023-2026.
3. Li H, Luan ZJ, Zheng GW, et al.Adv.Synth.Catal.2015, 357, 1692-1696.
