SyncoZymes

oloa

  • Ketoreductase (KRED)

    Ketoreductase (KRED)

    E uiga i le Ketoreductase

    Enzymes: O macromolecular biological catalysts, o le tele o enzymes o polotini.

    Ketoreductase: E taʻua foʻi o le "Carbonyl reductase", o enzymes e faʻamalosia ai le toe faʻafoʻiina o le redox i le va o aldehydes / ketones ma ava malosi, ma manaʻomia coenzymes e pei o le H transmitter e pei ole NADH poʻo le NADPH.E tolu vaega autu o KRED: Short-chain Dehydrogenase / Reductases (SDRs), Medium-chain Dehydrogenases / Reductases (MDRs), ma Aldo-KetoReductases (AKRs).O galuega fa'atino a le tolu e tutusa, ae o le fausaga ma meatotino e fai si eseese.

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  • Transaminase (ATA)

    Transaminase (ATA)

    E uiga i le transaminase

    ATA mai SyncoZymes: E 66 ituaiga o oloa enzyme ATA (Numera pei ES-ATA-101~ES-ATA-166) na atiaʻe e SyncoZymes.SZ-ATA o se meafaigaluega aoga e faʻapipiʻiina ai le faʻasologa o faʻalapotopotoga ma le stereoselective synthesis o chiral amines, amino acids ma a latou mea e maua mai i le tele o aliphatic ma aromatic ketoacids, aldehydes, ketones ma ketoses.

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  • Nitrilase (NIT)

    Nitrilase (NIT)

    E uiga i le Nitrilase

    ES-NITs: Faʻaliliu saʻo le vaega o le cyanide i le vaega o le carboxyl, e saunia ai le carboxylic acid, lea e masani ona faʻaaogaina i vailaʻau, puipuiga o le siosiomaga, vailaʻau vailaʻau, meaʻai faaopoopo, ie, gaosiga o faʻatoʻaga ma isi fanua.
    E 40 ituaiga o Nitrilase(NIT) oloa (Numera pei ES-NIT-101~ES-NIT-140) atiaʻe e SyncoZymes.O le ES-NIT ose meafaigaluega aoga e fa'apipi'iina ai le tu'ufa'atasiga o chiral carboxylic acids e ala i regio-ma stereoselective hydrolysis o le tele o aliphatic ma aromatic nitriles.

    Ituaiga tali fa'amamafa:

    Nitrilase NIT2

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  • Nitrile hydratase (NHT)

    Nitrile hydratase (NHT)

    E uiga i ES-NHTs

    ES-NHTs: o se vasega o metalloenzyme, lea e filifilia faʻamaʻaina nitriles i totonu ole amide muamua tutusa.E faʻaaogaina lautele e le gata mo le tuʻufaʻatasia o amino acids, amides, carboxylic acids ma a latou mea e maua mai ai, ae faʻapea foʻi mo le sauniuniga o vailaʻau chiral.E 24 ituaiga o nitrile hydratases na atia'e e SyncoZymes (Numera pei ES-NHT-101~ES-NHT-124).
    Ituaiga tali fa'amamafa:

    Nitrile hydratase NHT2

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  • Amidase (AMD)

    Amidase (AMD)

    AMD mai SyncoZymes: E 19 ituaiga AMD enzyme oloa (Numera pei ES-AMD-101~ES-AMD-119) atiaʻe e SyncoZymes.O le SZ-AMD ose meafaigaluega aoga e fa'apipi'iina ai le fa'asologa o fa'alapotopotoga ma le stereoselective synthesis o chiral carboxylic acids ma a latou mea e maua mai i ituaiga aliphatic ma aromatic amides.

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  • Ene reductase (ERED)

    Ene reductase (ERED)

    E uiga i le ene reductase

    ES-EREDs: E i ai i le aiga o enzymes samasama tuai e faʻaitiitia ai le C=C i le α, β -unsaturated faʻatasi ma vaega faʻapipiʻi eletise.E masani ona faʻaaogaina i le suʻesuʻeina o mea e maua mai i le amino acids, mea faʻaolaola, vailaʻau vailaʻau, mea manogi ma poloka chiral.

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  • Oxynitrilase (HNL)

    Oxynitrilase (HNL)

    E uiga i oxynitrilase

    ES-HNLs: Ose enzyme enantioselectively fa'apipi'iina le fa'aopoopoina o le HCN i aldehydes (ketones) e maua ai le R po'o le S type cyanide alcohols, lea e faigofie ona liua i le tele o ituaiga o vaila'au po'o vaila'au vavalo e ala i vaila'au.
    E 29 ituaiga o oloa oxynitrilase (Numera pei ES-HNL-101~ES-HNL-129) na atiaʻe e SyncoZymes.O le SZ-HNL o se meafaigaluega aoga mo le fa'aogaina o le (R)-cyanohydrins po'o le (S)-cyanohydrins mai le tele o mea manogi, aliphatic ma heterocyclic aldehydes po'o ketones.
    Ituaiga tali fa'amamafa:

    Oxynitrilase HNL2

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  • Nitro reductase (NTR)

    Nitro reductase (NTR)

    E uiga i le nitro reductase

    ES-NTRs: O flavoenzymes ia e faʻamalosia ai le faʻaitiitia o le NAD(P)H-faʻalagolago i vaega nitro i luga ole nitroaromatic ma nitroheterocyclic compounds ile hydroxylamino ma/poʻo amino derivatives.O loʻo faʻaaogaina lautele i le faʻaogaina o le hydroxylamine aromatic ma le aromatic amine, togafitiga o le tumo, suʻesuʻeina o meaola ma le faʻaleagaina o mea leaga o le siosiomaga.E 12 ituaiga o Nitro reductase (NTR) oloa (Numera e pei ES-NTR-101~ES-NTR-112) atiaʻe e SyncoZymes.

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  • Aldolase (DERA)

    Aldolase (DERA)

    ES-DERAs: E mafai ona fa'atupuina lelei le fa'aopoopoina fa'apitoa o ketone foa'i i le tali atu o aldehydes.E le gata i lea, o le tali e mafai ona faia i le vai vaifofo o le pH le mautonu e aunoa ma ni puipuiga faapitoa.Latou te auai i le vasega I aldolase, lea e fausia ai le faavae Shiff i le faagasologa catalytic.O le substrate o loʻo faʻapipiʻiina faʻatasi ma le vaega amino o le nofoaga galue e amata ai le malepelepe ma le faʻavaeina o le fusi.O le eseesega i le va o DERA ma isi aldolase o mea'ai latou te fa'auluina o aldehydes ma e mafai ona fa'aauau pea le condensation aldehydes.

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  • Cytochrome P450 monooxygenase (CYP)

    Cytochrome P450 monooxygenase (CYP)

    E uiga ile CYP

    ES-CYPs: O se vasega o redox enzymes ma mercaptan-heme e avea ma nofoaga autu e faʻamalosia ai le faʻafeiloaʻi o le okesene.O okesene fa'agata ma e mana'omia le heme e fa'agaoioi ai le okesene.

    Cytochrome P450 monooxygenase faʻamalosia le faʻamaʻiina, epoxidation ma le hydroxylation o alkyl, hydroxylation ma le faʻamaʻiina o le ammonia, faʻamaʻiina o le sulfur, dealkylation (oxygen, sulfur, ammonia), oxidative dehydrogenation, deamination ma dehalogenation.
    E 8 ituaiga o cytochrome P450 monooxygenase oloa (Numera pei ES-CYP-101~ES-CYP-108) atiaʻe e SyncoZymes.

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    I-Meli:lchen@syncozymes.com

  • Alcohol oxidase (AOX)

    Alcohol oxidase (AOX)

    E uiga i le alcohol oxidase

    ES-AOXs: O nei enzymes e mafai ona fa'aosoina le fa'ama'iina o ga'o 'ava malosi po'o aryl-alcohols e fausia ai le aldehydes.Latou te fa'aogaina le okesene mole mole ae le mana'omia se mea fa'aopoopo mai fafo, ma gaosia le hydrogen peroxyide.

    E 6 ituaiga o oloa e gaosia ai le ava malosi (Numera e pei ole ES-AOX-101~ES-AOX-106) na fausia e SyncoZymes.O le ES-AOX101 ma le ES-AOX102 e sili atu i mea'ai o le aliphatic alcohol, ES-AOX103~ ES-AOX105 e sili atu i mea manogi o le ava malosi, ma le ES-AOX106 o le cholesterol oxidase.O le SZ-AOX ose meafaigaluega aoga e fa'afefe ai le fa'ama'iina o ga'o 'ava malosi po'o aryl-alcohols e maua ai le aldehydes.

    Ituaiga tali fa'amamafa:

    AOX

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    I-Meli:lchen@syncozymes.com

  • D-Amino acid dehydrogenase (D-AADH)

    D-Amino acid dehydrogenase (D-AADH)

    E uiga i le D-Amino acid dehydrogenase

    ES-D-AADH (D-Amino acid dehydrogenase): o se enzyme e mafai ona faʻaititia le 2-keto acid i le D-amino acid tutusa.Ole tali e mana'omia le NADP(H) ma le fa'ameamea ole ammonia foa'i (e pei ole ammonia po'o le ammonium ion).E 17 ituaiga o D-amino acid dehydrogenases (Numera pei ES-DAADH-101~ ES-DAADH-117) atiaʻe e SyncoZymes.

    Ituaiga tali fa'amamafa:

    D-Amino acid dehydrogenase2

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